Principal Investigator
gbassel@emory.edu
Postdoctoral Fellow
bart.anderson@emory.edu
I am interested in translational control and the function of non-coding RNAs and how defects in these processes contribute to human disease. Specifically, to better understand fragile X syndrome (FXS), I am investigating how the fragile X mental retardation protein (FMRP) interacts with miRNAs and the RISC complex to regulate translation of target mRNAs.
Graduate Student (Ph.D. program, Neuroscience)
numen1104.chou@gmail.com
Graduate Student (Ph.D. program, BCDB)
pdonlin@emory.edu
Assistant Professor
cgross3@emory.edu
My research is focused on the molecular mechanisms leading to synaptic defects that are observed in fragile x syndrome (FXS). I am especially interested in how the translational dysregulation of specific target mRNAs in the absence of the Fragile X Mental Retardation Protein (FMRP) in FXS might lead to exaggerated signal transduction through group I metabotropic glutamate receptors. Using pharmacologic as well as genetic approaches, I am currently investigating potential strategies to rescue these cell signaling defects at FMRP deficient synapses.
Postdoctoral Fellow
alicia.l.hawthorne@emory.edu
I am interested in promoting axonal regeneration after spinal cord injury through mRNA binding proteins, such as ZBP1. mRNA binding proteins are important for local protein translation in the growth cone and for forward growth. By enhancing the growth capabilities of axons we may be able to promote successful regeneration through the inhibitory environment after CNS injury.
Postdoctoral Fellow
mariusifrim@emory.edu
I am interested in local protein synthesis regulation at the synapse and how this is affected in neuro-developmental disorders. My current project is focused on studying the perturbations of local protein synthesis in a mouse model of Fragile X Syndrome, using a single-molecule microscopy approach.
Lead Research Specialist
lli35@emory.edu
I do research on the SMA disease protein SMN, together with Dr. Rossoll.
Assistant Professor
Associate Director, Integrated Cellular Imaging (ICI) core
mattheyses@emory.edu
Lead Research Specialist
ashwini.poopal@emory.edu
My research is focused on studying dysregulated protein synthesis and PI3K Pathway in FXS (Fragile X Syndrome) patient lymphoblastoid cell lines, together with Dr. Christina Gross.
Graduate Student (Ph.D. program, Neuroscience)
nraj2@emory.edu
Assistant Professor
wrossol@emory.edu
My main research interest is the role of mRNA transport and local translation in the regulation of axon growth. My emphasis is on the function of the spinal muscular atrophy (SMA) disease protein SMN and the amyotrophic lateral sclerosis (ALS) disease protein TDP-43 in the development and maintenance of motor neurons.
Research Specialist
rowe.latoya@emory.edu
I do research on the ALS disease protein TDP-43, together with Dr. Rossoll.
Graduate Student (Ph.D. program, Neuroscience)
ktthoma@emory.edu
.
Graduate Student (Ph.D. program, BCDB)
krwill7@emory.edu
I am interested in the biological role of mRNA binding proteins associated with SMN in development.
